northwestern microfluidics

The device won an innovation award at this year's CES convention in Las Vegas. As featured in The New York Times, Northwestern Engineering's John Rogers has developed a new microfluidic device that analyzes a person's sweat composition to provide real-time feedback on their health and fitness performance. In this paper, we describe an innovative modular microfluidic platform allowing filtering, concentration and analysis of peptides from a complex mixture. PhD Student. Dr. Julio M. Ottino is currently Dean of the Robert R. McCormick School of Engineering and Applied Sciences at Northwestern University and holds the titles of Distinguished Robert R. McCormick Institute Professor and Walter P. Murphy Professor of Chemical and Biological Engineering. Research Statement: Working on new reconstruction algorithms to improve the quality of x-ray images and developing instrumentation in x-ray microscopy for mm to cm samples. But the sheer size of the external equipment required for controlling these quarter-sized devices has limited their use in portable, wearable technologies. This article describes a microfluidic device that has three inputs and performs 2592 distinct enzyme reactions using only 150 L of reagent with quantitative characterization. Using Microfluidic Devices to Model and Investigate Leaky Gut Syndrome Public Deposited. 633 Clark Street. Email address. Prior to joining the Northwestern faculty in March 2006, he held positions as Guest Scientist at the Max Planck Institute for the Physics of Complex Systems, Germany, and as Director's Funded Postdoctoral Fellow at the .

Galter Pavilion 675 N. St. Clair, 21st Floor Chicago, IL 60611. Microfluidics experience; Benefits: At Northwestern, we are proud to provide meaningful, competitive, high-quality health care plans, retirement benefits, tuition discounts and more! A multi-layer approach segregates components belonging to two fundamental categories: passive fluidic components (channels and reaction chambers) and active electromechanical control structures (sensors and actuators). However, at very small scales (on the order of 100 microns and less) electrostatic forces at charged interfaces can actually drive fluid flow. Northwestern University is an Equal Opportunity, Affirmative Action Employer of all protected classes, including veterans and individuals with disabilities . 866-LURIE-CC or 312-695-0990. Chicago . Northwestern University

. Newer platforms also quantify concentrations of heavy metals such as lead and arsenic and urea and creatinine levels, the latter of which relates to kidney health. A Northwestern University-led research team has developed a novel skin-mounted sticker that absorbs sweat and then changes color to provide an accurate, easy-to-read diagnosis of cystic fibrosis within minutes. Microfluidic biodisks take advantage of noninertial pumping for lab-on-a-chip devices using noninertial valves and switches under centrifugal and Coriolis forces to distribute fluids about the disks. Founded: 2017. Electrophoresis, the motion of charged . Now Northwestern University researchers "Microfluidic systems have the power to revolutionize medicine, energy, electronics and even space exploration. Northwestern Resources. Credit: Northwestern University "Ice it . The candidate will join a dynamic research team that has pioneered microfluidic technology for the study of reproductive tissues. The device is described as a soft, miniaturized, implantable nerve cooling system that is based on "state-of-the-art microfluidic and flexible electronic technologies." S Shiva P Nathamgari PhD, Theoretical and Applied Mechanics, Northwestern University Verified email at u.northwestern.edu. Discover the role of microfluidics and microfluidic technology in analytical chemistry. . . 19 years of excellence 2145 Sheridan Road - Tech Institute A173 Evanston, IL 60208 | 847.467.2318 www.nuance.northwestern.edu Exploring Inner Space . 312-503-6303. Our most active areas are in neurotechnologies and in biomedical . A little larger than a quarter and about the same thickness, the simple . Robert H. Lurie Comprehensive Cancer Center of Northwestern University Clinical Cancer Center. Evanston, IL 60208. Adilson E. Motter is the Charles E. and Emma H. Morrison Professor of Physics and Astronomy at Northwestern University. The systems were first deployed on triathletes and are now routinely used by Northwestern's swimming team.

In a recent study, the researchers discovered how to pre-program the devices' network . Current areas of emphasis include conformal electronics, nanophotonic structures, microfluidic devices, and microelectromechanical systems, all with an emphasis on bio-inspired and bio-integrated technologies. Follow Hunter on LinkedIn. In SI units a micro-meter ( m) or micron refers to a millionth of a meter. sweat) extraction, capture, and analysis in real time, outside of controlled laboratory environments. ', Clinical chemistry Clinical chemistry In January 2022, she joined the Stoddart Group at Northwestern University as a Postdoctoral Fellow. These findings can be used to create built-in control mechanisms, thereby facilitating the development . A skin pH measuring device developed by Northwestern researchers and L'Oral. AU - Hernandez, Vivian M. AU - zdinler, P. Hande. I am particularly interested in problems in biology such as the interaction of biological membranes with fluid flow and electric fields. "Current microfluidic technology often requires a desktop full of equipment to operate something the size of a quarter," said Northwestern's Adilson Motter, senior author of the study.

The first-of-its-kind device could provide a much-needed alternative to opioids and other highly addictive medications. Recent work has focused on problems in microfluidics and soft matter theory. Address.

Northwestern University researchers have discovered how to pre-program microfluidic systems in a way that controls how fluids flow and mix throughout the micropipes. The role of the Segal Prototyping and Fabrication Lab is to provide an opportunity through design to move from theory to practice in a safe and supportive learning environment. crs@northwestern.edu.

Northwestern University is an Equal Opportunity, Affirmative Action Employer of all . 2 To put this in perspective, the average width of a human hair is about 80 microns and the diameter of a hydrogen atom is 0:00005 micron. The dual PhD, or co-tutelle de thse, is an ad hoc agreement that allows outstanding students with specific interests and needs to have their PhD dissertation supervised by faculty members from both Northwestern and a French university. Now Northwestern University researchers are pushing microfluidics closer to reaching its true potential. Microfluidics has high-throughput, quantitative, and small-scale benefits for engineering, physics, chemistry, biology, materials science, and biotechnology.

granular dynamics, microfluidics, geophysical sciences . Northwestern Microfluidics Engineering and Maintenance Team Hunter Rogers, M.S. A microfluidic and electronic system for cooling and simultaneously measuring nerve temperature was designed as an implement to "ice"" away pain. Source: Northwestern University Address. I am currently working to improve automated diagnosis of acute respiratory distress syndrome ( ARDS ) using machine learning on radiologist reports, with the . . In fiber optics, we developed and commercialized classes of devices that provide tunable operation for chromatic dispersion compensation for high-speed, wavelength-multiplexed lightwave communication systems. Research: High-Throughput, Cell-Based Assays with SAMDI; Megamolecule-Based Imaging Agents and Therapeutics for Cancer and Alzheimer's Disease Eric is using SAMDI to evaluate large libraries of nanomaterials in order to discover design rules governing cancer vaccine efficacy. Ph.D. Upon joining the Stoddart Group at Northwestern University as a Postdoctoral Fellow in January 2022, Ruihua will . Northwestern Undergraduate Research Journal; Items. Department of Materials Science. Inspired by his undergraduate research experience, Cesar joined Prof. Horacio Espinosa's laboratory at Northwestern University to pursue a PhD degree in Mechanical Engineering. To do this we combine live-cell imaging, microfluidics, and single-cell RNA-Seq to generate a quantitative profile of immune cell behavior. McCormick School of Engineering and Applied Science. Watch on. He is pairing SAMDI with microfluidics and localized electroporation to temporally measure cellular responses. To induce the cooling effect, the device contains tiny microfluidic . Epicore Biosystems creates soft microfluidics devices that harvest and route sweat from skin pores. However, recording of time-dependent variations in sweat composition requires bulky electronic systems and power sources, thereby constraining form factor, cost, and modes of use. NUFAB has a wide variety of utilizing tools for microfluidic fabrications. September 2016. April 2021: Collaborative work between previous group members Jian Zhang, Won-Kyu Lee, and Dongjoon Rhee and Hangzhou Dianzi (University in China), "Spontaneous Formation of Ordered Magnetic Domains by Patterning Stress . News & Press Mentions. The lab is available to students and faculty in support of their educational project work and is staffed by lab professionals and student lab leaders who are skilled in . Electroosmosis has important applications in microfluidics and nanotechnology. Center for Bio-Integrated Electronics, Northwestern University, Evanston, IL, 60208 USA. In this project, we are developing collections of ideas in materials science and device design to create biocompatible classes of microsystems technologies, with uses in biological research and clinical medicine. The microfluidic device harmlessly dissolves once it's no longer needed Northwestern University Nobody wants to suffer physical pain if they don't have to, yet they also don't want to risk . This work combines fundamental studies with forward-looking engineering efforts in a way that promotes positive feedback between the two. I am particularly interested in problems in biology such as the interaction of biological membranes with fluid flow and electric fields. I was fortunate to be on this big UH3 project on modeling PCOS in microfluidics with a lot of CRS members like Dr Kim, . 2 School of Aeronautics, Northwestern Polytechnical University, 127 West Youyi Rd., Xi'an, Shaanxi, China and Queensland Micro- and . "In 10 years, this technology, called microfluidics, will be the prevailing technology for biological research." For more information, check out the following video. Our work on optical coherence tomography and microfluidics sorting is featured by OCT News as Feature of the Week (10/13/2016). northwestern.edu High-Throughput Regulatory Part Prototyping and Analysis by Cell-Free Protein Synthesis and Droplet Microfluidics . The result? However, optical detection methods limit analyses to fluorescent or UV-active compounds and traditional 2D fluidic designs have limited degrees of freedom. 633 Clark Street. . john a. kessler Northwestern Univeristy . Northwestern researchers' pain relief device is about 5 millimeters wide and as thin as a sheet of paper, flexible and soft enough to wrap around nerves without causing damage.

Lorem ipsum dolor sit amet, consectetur adipiscing elit. The present global pandemic draws attention to the importance of rapid sample-to-answer PoC devices for . 312-503-6303. Wearable Technology. Email address. However, measuring reaction progression in these small devices is hindered by available readout methods, which typically rely on fluorescent products. McCormick. Bio. Panpan Huang. His current research focuses on the design and manufacturing of microfluidic devices to nondestructively extract molecules from live cells for analysis. Photo credit: H. Luan, Northwestern University. Bio-Integrated Electronics, Optoelectronics, Microfluidics and MEMS. A Northwestern University-led team of researchers has developed a small, soft, flexible implant that relieves pain on demand and without the use of drugs. Department of Biomedical Engineering. Recent work has focused on problems in microfluidics and soft matter theory. Northwestern Inventor: John Rogers. The project involves using 3D endometrial ex vivo models to study the influence of a PCOS ovary in a microfluidic platform. 645 N. Michigan Ave., Suite 630 Chicago, IL 60611. 15th International Conference on Miniaturized Systems for Chemistry and . Each facility serves specific users and types of work, and can only be accessed after undergoing training and agreeing to comply to user policies. One such device, created by John Rogers' lab at Northwestern University, is a battery-free continuous . He has published over 300 technical papers in these topics. Accessibility; TY - CHAP. publisher = "American Association for Clinical Chemistry Inc.", number = "2",} Delaney, SR & Suh-Lailam, BB 2018, ' Microfluidics: The future of testing? Rogers's soft, flexible device rests on the skin and is composed of an intricate array of tiny channels and . Applications are invited for a Postdoctoral Research Associate in nanomechanics and metamaterials at the Micromechanics and Microfluidics Lab. Examples of such electrokinetic effects include electroosmosis and electrophoresis. Abstract Microfluidic laboratory-on-a-chip (LOC) systems based on a modular architecture are presented. panpanhuang2015@u.northwestern.edu. Candidate, Obstetrics & Gynecology, Northwestern University. Phone number. . Theory of Stokes-flow. Querrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL, 60208 USA.

A Northwestern University research team has developed a first-of-its-kind soft, flexible microfluidic device that easily adheres to the skin and measures the wearer's sweat to show how his or her body is responding to exercise. A Northwestern University research team has developed a first-of-its-kind soft, flexible microfluidic device that easily adheres to the skin and measures the wearer's sweat to show how his or her body is responding to exercise. In a recent study, the researchers discovered how to pre-program the devices' network . Address. The student then receives a doctorate from the French institution and a PhD from Northwestern.. With advisors on both sides of the Atlantic and opportunities .

Microfluidic devices represent an exciting emerging technology that allow for high-throughput analysis of miniaturized reactions, potentially conserving expensive reactant quantities. Here, we report a microwell array format live-cell analysis device (LCAD) that can perform localized-electroporation induced membrane . EVANSTON - A Northwestern University research team, led by John Rogers, has developed a first-of-its-kind soft, flexible microfluidic device that easily adheres to the skin and measures the wearer's sweat to show how his or her body is responding to exercise. Figure S8B and Fig. Group: Jacobsen Group. Micro uidics is the science of manipulating uids on spatial scales anywhere between one to a hundred micron. As described in detail in Materials and Methods, fabrication of this construct begins with formation of a 2D microfluidic system in PDMS . McCormick School of Engineering and Applied Science. These two microfluidic structures flank either side of the patch. This paper demonstrates a simple microfluidic device that incorporates a functionalized self-assembled monolayer to measure the rate constant for a chemical reaction.

A step toward smartly designed microfluidic systems that behave like a computer chip without relying on external components. Lab-on-a-Disc (LoaD) biosensors are increasingly a promising solution for many biosensing applications. Roozbeh Ghaffari. Catalog description The objective is to give students an introduction to the essential fluid mechanical concepts needed to work in some of the most contemporary areas of mechanical engineering: microfluidics, nanotechnology, nanoscale materials, MEMS, nano-biotechnology, etc. Nondestructive cell membrane permeabilization systems enable the intracellular delivery of exogenous biomolecules for cell engineering tasks as well as the temporal sampling of cytosolic contents from live cells for the analysis of dynamic processes. Office location: Tech F222. T2 - Novel tools and future implications. In the search for a perfect match between point-of-care (PoC) microfluidic devices and biosensors, the LoaD platform has the potential to be reliable, sensitive, low-cost, and easy-to-use. Her graduate research encompassed single-cell protein analysis based on microfluidics, on-chip electrocatalysis of two-dimensional materials, and single-crystal electrical transport of nanoclusters and Metal-Organic Frameworks. Hunter employed and managed the microfluidic technology, and led the engineering team at NU.

After working in microfluidics and tissue engineering, I decided to get busier with computers and data. Various lab-on-a-chip applications can only be realized if droplets are systematically categorized and sorted. .

T1 - Microfluidics for neuroscience. One such technology is normalizing and increasing the use s of microfluidic devices. Recent developments in skin-integrated soft microfluidic systems address many challenges associated with standard technologies in sweat collection and analysis. We are working hard to serve micro/nano fabrication in research. 5D highlight the multimodal microfluidic substrate and chrono-sampling features of the system. May 2021: Tad's article, "Ultrafast Spectroscopy of Plasmonic Titanium Nitride Nanoparticle Lattices," has been published in ACS Photonics. Since receiving his Ph.D. he has worked as a senior researcher at MIT, Massachusetts General Hospital, and MC10 Inc. 3D hybrid microfluidic and electronic systems in the form of extended, interconnected 4-by-4 double-floor helical arrays of 3D microvascular networks with . BioCDs use spinning-disk interferometry, under the condition of common-path phase quadrature, to perform interferometric label-free detection of . "We took the control that's provided by external systems and built it into the device's structure." The study was published today (Oct. 23) in the journal Nature. Search for more papers by this author. Khvostichenko, DS, Perry, SL, Kondrashkina, E, Guha, S, Brister, K & Kenis, PJA 2011, Microfluidic platforms for on-chip formulation and small-angle X-ray analysis of the phase behavior of lipid/water mixtures. Fusce aliquam porta venenatis. Now Northwestern University . Evanston, IL 60208. In our recent Nature article, we design microfluidic networks whose behavior can be harnessed to create a fluid analogue of Braess's paradox and switch the direction of internal flows solely by manipulating the input and/or output pressures. Espinosa is a mechanician and nanotechnologist known for his contributions in the areas of deformation and failure of materials, design of micro- and nano-systems, and microfluidics for single cell manipulation and analysis.

Northwestern University. Machine shops and prototyping labs house equipment for the development of physical and electrical prototypes, with capabilities ranging from wood & hand tools to CNC and 3D-printed components. Phone number: 847-467-0218. Our early work in microfluidic optical fiber helped to establish the field of optofluidics. Northwestern University Feinberg School of Medicine.

PY - 2012/1/1 Earlier designs measured chloride loss, glucose, lactate and pH levels in sweat. A flexible magnetic loop antenna, a set of near-field communication (NFC) components, and a light-emitting diode (LED) as a mode for user notification form a wireless interface to NFC-enabled devices (smartphones, tablets, etc) for transmitting digital identification codes and for reading skin . Northwestern University.

The ability to manipulate and sort droplets is a fundamental issue in droplet-based microfluidics. The possibility of coupling such technologies with soft hydrogels and thin, low-modulus microfluidic platforms allows conformal interfaces to the epidermis to facilitate fundamentally differentiated ambulatory modes for biofluid (i.e. These microfluidic design features appear in other, previously reported devices for sweat collection and analysis. Analytics. Danijela Dokic, M.D. Thumbnail Title Date Uploaded Visibility Actions; CAURS_2020_BasteJ____1_.docx: 2020-06-27: Public: Press to Select an action Download Imaging Neurons with Microfluidic Chambers. Northwestern Resources. Collaborative research to study brain tumors using our new super-resolution imaging technoogy received $120k seed fund from Northwestern Innovative Initiatives Incubators (I3) interdisciplinary program.

Circular holes (diameter, 1 mm) serve as inlets in the base of . Content The molecular basis of fluid mechanics. Photo credit: P. Gutruf, Northwestern University. Danny Vesurai , Reporter Her graduate research encompassed single-cell protein analysis based on microfluidics, on-chip electrocatalysis of two-dimensional materials, and single-crystal electrical transport of nanoclusters and Metal-Organic Frameworks. As such, I am a student in the Quantitative and Systems Biology master's program.

His work has advanced the fields of microfluidics, BioMEMS, biomechanics, and cellular physiology through a combination of instrumentation, imaging, software, and computational modeling. Initially introduced in 2016, Rogers' microfluidic design has come a long way in the past year.

. Northwestern University - Cited by 101 - Microfluidics - BioMEMS - Electroporation - Intracellular Delivery - Single Cell Analysis . Address. The platform is composed of a microfluidic filtering device and a superhydrophobic surface integrating surface enhanced Raman scattering (SERS) sensors.

If you think you would be a good match with our lab, don't hesitate to contact Prof. Horacio D. Espinosa for more information at espinosa@northwestern.edu. A Northwestern University research team has developed a first-of-its-kind soft, flexible microfluidic device that easily adheres to the skin and measures the wearer's sweat to show how his or her body is responding to exercise. Phone number. .

. While measuring chloride levels in sweat to diagnose cystic fibrosis is standard, the soft, flexible . . . in 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011. Now Northwestern University researchers are pushing microfluidics closer to reaching its true potential. crs@northwestern.edu. New adhesive materials and microfluidic designs maintain water-tight seals to the skin to capture and analyze sweat while preventing surrounding water from entering the device's microscopic channels. 645 N. Michigan Ave., Suite 630 Chicago, IL 60611.

Morbi semper sollicitudin placerat. . Managerial Analytics (KELLG_MA) Materials Science & Engineering (MAT_SCI) Math Methods in the Social Sciences (MMSS) Mathematics (MATH) Mechanical Engineering (MECH_ENG) Middle East and North African Studies (MENA) Music (MUSIC) Music Composition (MUS_COMP) Music Education (MUSIC_ED) A little larger than a quarter and about the same thickness, the simple, low-cost device, described in the journal . Proin pellentesque mauris non diam viverra tincidunt elementum justo pharetra. The device mixes the reactants and allows them to selectively immobilize to the monolayer at the base of a microfluidic channel in a time-dependent manner as they flow down the . The sweat sensor channel resides in between the regions for electrochemical and colorimetric sensing.

northwestern microfluidics